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NMN Clinical Trials


Human/animal clinical trials related to NMN

2022年8月 Supplementation of nicotinamide mononucleotide improves the quality of postovulatory aged porcine oocytes

2022年8月 Nicotinamide mononucleotide ameliorates DNFB-induced atopic dermatitis-like symptoms in mice by blocking activation of ROS-mediated JAK2/STAT5 signaling pathway

2022年7月 Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE

2022年7月 Combination of nicotinamide mononucleotide and troxerutin induces full protection against doxorubicin-induced cardiotoxicity by modulating mitochondrial biogenesis and inflammatory response

2022年7月 Administration of nicotinamide mononucleotide improves oocyte quality of obese mice

2022年7月 Nicotinamide Mononucleotide and Coenzyme Q10 Protects Fibroblast Senescence Induced by Particulate Matter Preconditioned Mast Cells

2022年6月 Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice

2022年6月 Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis

2022年6月 Metformin, Rapamycin, or Nicotinamide Mononucleotide Pretreatment Attenuate Cognitive Impairment After Cerebral Hypoperfusion by Inhibiting Microglial Phagocytosis

2022年6月 Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment

2022年6月 Nicotinamide mononucleotide supplementation improves the quality of porcine oocytes under heat stress

2022年6月 Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3-Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury

2022年6月 Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells

2022年6月 Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling

2022年5月 The combination of nicotinamide mononucleotide and lycopene prevents cognitive impairment and attenuates oxidative damage in D-galactose induced aging models via Keap1-Nrf2 signaling

2022年5月 Nicotinamide Mononucleotide Administration Amends Protein Acetylome of Aged Mouse Liver

2022年5月 Distribution of Nicotinamide Mononucleotide After Intravenous Injection in Normal and Ischemic Stroke Mice

2022年5月 Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPR mt

2022年5月 The combination of nicotinamide mononucleotide and lycopene prevents cognitive impairment and attenuates oxidative damage in D-galactose induced aging models via Keap1-Nrf2 signaling

2022年4月 NAD + Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy

2022年4月 NAD +-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice

2022年4月 Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency

2022年4月 Treatment of SARS-CoV-2-induced pneumonia with NAD + and NMN in two mouse models

2022年4月 Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects

2022年4月 The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions

2022年4月 NAD + Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy

2022年4月 Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress

2022年4月 Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes

2022年4月 NAD+ ameliorates endotoxin-induced acute kidney injury in a sirtuin1–dependent manner via GSK-3β/Nrf2 signalling pathway

2022年4月 Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment

2022年4月 Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice

2022年4月 NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages

2022年4月 NAD supplementation improves mitochondrial performance of cardiolipin mutants

2022年3月 Antioxidant effect of nicotinamide mononucleotide in tendinopathy

2022年3月 Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing

2022年3月 Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy

2022年3月 Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1/Nrf2/HO-1 pathway

2022年2月 Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study

2022年2月 PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease

2022年1月 Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns

2022年1月 NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury